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As for clinical outcomes, in the T2DM group, there was a significant reduction in HbA1c (decreased by 1.01% to 1.02%, placebo-adjusted) and a clinically meaningful decrease in body weight of 3.26% to 3.51% after 12 weeks of treatment

Impact of Sodium Glucose Cotransporter 2 (SGLT2) Inhibitors on Atherosclerosis: From Pharmacology to Pre-Clinical and Clinical Therapeutics

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doi: 10.1016/j.bcp.2018.07.021 67 GeislerCEAntonellisMPTrumbauerWMartinJACoskunTSammsRJet al