glp 1 agonist in pregnancy From JAMA: #GLP-1 receptor exposure with discontinuation before or during early #pregnancy was associated with greater gestational weight gain and increased risk of preterm delivery, gestational #diabetes, and hypertensive disorders. https://ja New developments in GLP-1 agonist

The class of medications known as GLP-1 receptor agonists simply mimics that natural hormone, including tirzepatide, liraglutide, and semaglutide the oldest of the drugs, best known by brand names Ozempic or Wegovy

Both the 2016 consensus statement of the American Association of Clinical Endocrinologists and American College of Endocrinology (AACE/ACE) on management of type 2 diabetes and the 2016 American Diabetes Association (ADA) standards recommend adding on GLP-1 RAs to patients not meeting treatment goals with basal insulin

Clinical trials UNC (University of North Carolina) School of Medicine conducted a phase 2 clinical trial to examine semaglutides effects on people with alcohol use disorder

2.2 Rat studies Studies with laboratory rats were conducted in accordance with the standards of the Federal Republic of Germany (similar to AAALAC equivalents) under license numbers SYN01/16, SYN07/20, and SYN01/22, provided by the Regierungsprsidium Tbingen ethics committee

[DOI] [PMC free article] [PubMed] [Google Scholar] 59.Di Rosa C., Lattanzi G., Spiezia C., et al

According to public FDA communications, the semaglutide drug shortage has been officially resolved as of February 2026