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Such widespread usage has led to a severe and prolonged international shortage of these drugs 13,14 , with consequent lack of access to treatment for patients with diabetes 15 and the urgent need to issue guidelines for alternative treatments 16

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Therapeutic effects on the development of heart failure with preserved ejection fraction by the sodium-glucose cotransporter 2 inhibitor dapagliflozin in type 2 diabetes
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In contrast, the seven-day, 14-day, and 30-day cohorts had no independent risk factor for delayed emergence from anesthesia