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Effects of Weight Loss on Lean Mass, Strength, Bone, and Aerobic Capacity. Medicine and Science in Sports and Exercise , vol

Interestingly, in a retrospective study of 186 patients (56% type 1 diabetes mellitus) from the Netherlands, dyspeptic symptoms, with the exception of early satiety and abdominal pain, were unrelated to delayed gastric emptying [69]

A randomized clinical trial comparing the effect of once-daily treatment of liraglutide and once-weekly treatment of semaglutide showed that adult patients treated with semaglutide for 68 weeks showed more than twice the decrease in body weight compared to people treated with liraglutide [80]

Despite these advances, several controversies remain unresolved

Anti-obesity drug discovery: Advances and challenges

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