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A new study found that the cost of GLP-1 drugs like Wegovy and Zepbound is too high to justify their benefits

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Based on this review, evidence from head-to-head and insulin-comparator trials demonstrates that dual GIP/GLP-1 co-agonism consistently overcomes metabolic plateaus that result from single-pathway therapy, producing superior glycated hemoglobin reduction, bariatric-level weight loss (up to 25.3%), and robust macrovascular and heart failure protection, including a 38% reduction in composite cardiovascular risk among patients with heart failure with preserved ejection fraction (HFpEF)

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In a new Journal of American Chemical Society study, Krishna Kumar, Martin Beinborn, and co-workers from Tufts University unveil the first unimolecular tetra-agonistspeptides that activate GLP-1R, GIPR, GcgR, and Y2R all at once