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Frias JP, Hsia S, Eyde S, Liu R, Ma X, Konig M, et al
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Rodriguez PJ et al

[DOI] [PubMed] [Google Scholar] 8

Further supporting a direct GLP-1 inhibition of glucagon secretion is the fact that such secretion is not prevented in isolated human islets treated with the insulin receptor antagonist S961 or the somatostatin receptor 2 antagonist CYN154806 [608]

According to him, tracking, monitoring, and optimizing this risk reduction is critical to reducing the complications of cardiovascular-kidney-metabolic disease. However, as with other GLP-1 receptor agonists, orforglipron carries safety considerations
