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45 en un modelo polignico de ratas con obesidad y DM2 reportaron que los animales en tratamiento con la liraglutida presentaron una reduccin sostenida de la ingesta de alimentos y un menor porcentaje de masa grasa corporal en relacin con animales en control mantenidos con alimentacin restringida que presentaron la misma prdida de peso, lo que sugiere un efecto del incretino mimtico en la distribucin de grasa corporal

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