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Semaglutide acts like natural GLP-1

When researchers compared it to eating chicken, they saw a significantly decreased calorie intake during the mycoprotein meal that was not compensated for later in the day, which led to an average caloric reduction over the whole day by 188 calories

10.1007/s10561-022-10021-9 122

Kober, H

20 , 21 GLP-1 receptors are also expressed in peripheral structures such as the carotid body, where they may dampen chemoreflex-driven sympathetic activation, 22 , 23 although this reduced activation has yet to be confirmed in human studies

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