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GLP-1 medicationsincluding household names like Ozempic, Wegovy, Byetta, and Victozamimic a natural hormone your gut produces after eating, called GLP-1 (short for glucagon-like peptide-1)

New-generation 5-HT4 agonists have high selectivity for 5-HT4 receptors, with little affinity for other serotoninergic and other classes of receptors [53]

Lancet Diabetes endocrinol (2021) 9(10):65362

Sharon Fruh: Served on advisory board for Novo Nordisk

Metabolism (2020) 109:154272

Co-agonism showed, on murine models, the capability to improve insulin secretion and sensitivity in a weight-dependent and weight-independent manner, probably through its action on nutrient metabolism (49, 50), preventing their accumulation and thus making these organs actively involved in metabolism with an improvement in insulin sensitivity and WL, yielding long-lasting effects