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Using an integrated ligand and structure-based virtual screening pipeline, explicitly combining complementary ligand-based descriptors, multi-fingerprint similarity, electrostatic similarity, pharmacophore modeling, and multi-conformation docking under a consensus-driven selection strategy, we were able to identify three chemically distinct classes of GLP-1R agonist candidates: GQB47810, a non-peptidic molecule

Revisiting our GLP-1 Basket

For years, people have been trying all sorts of methods []

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Rapid weight loss can mean losing water, fat, and muscle

A study of health insurance claims found a 44% reduction in hospitalizations for GLP-1 users