glp 1 drug class Dosage of GLP-1 analogues How underwriters should interpret GLP-1
Description
Your health goals and preferences Whether youre interested in GLP-1s or SGLT2 Inhibitors, remember that each medicine has different routes of administration, side effects, duration of action, costs, and effects on weight and A1C level

The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans
Three of the four exenatide studies compared the odds of having pancreatitis requiring hospitalization relative to patients using other diabetes medications, and identified 1-year incidence rates from 0.132% to 0.196% versus 0.133% to 0.249% in comparison patients

Based on the strength of the clinical data, we expect Wegovy to be added to formularies with utilization management restrictions for prior authorization to prevent off-label use, shorter initial approval periods (e.g., six months approved initially) to ensure efficacy, and quantity limits to reduce stockpiling and waste

Declines were even more pronounced among households with GLP-1 weight loss users, who decreased food spending six times faster than non-GLP-1 households (-3%)
Qsymia or Contrave are your oral options until oral GLP-1 formulations for weight loss become widely available
