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Quick Answer: Weaning off tirzepatide without weight regain requires medical supervision for potential dose tapering, intensified lifestyle modifications including 200300 minutes weekly of physical activity, protein-optimized nutrition, behavioral strategies like regular self-weighing, and realistic expectations about the biological tendency toward weight regain after discontinuation

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My approach has been to go with the cost effective GLP, BUT not have all my eggs in one basket and make sure we have additional strategies in play

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