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Other emerging competitors in the pipeline Retatrutide and Mounjaro are not the only players in this space

Although part of the same drug class as Wegovy , Zepbound differs slightly from other GLP-1 medications in that it targets two hormone receptors: glucagon-like peptide-1 (GLP-1) and glucagon-like peptide-1 (GIP)

Tirzepatide promotes cAMP generation while minimally recruiting -arrestin, which reduces receptor internalization and extends surface signaling duration 35

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The conversion to traditional approval was granted based on an additional 123 patients and 25 months of further follow-up