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Observations in rodent models include changes in metabolic biomarkers, hepatic lipid levels, and gene expression patterns related to energy metabolism [5]

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Snyder, M.D

Why might these need to be factored in

in humans, an association between sDPP-4 and triglyceride levels was evidenced, while patients treated for 24 months with a DPP-4is-based combination with metformin exhibited an improved lipid profile, especially for triglycerides and LDL, when compared to baseline in T2D patients [67]

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