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Why does semaglutide max out at 2.4 mg while tirzepatide goes to 15 mg

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Moreover, GLP-1 changes in healthy participants and individuals with obesity were negatively correlated with anticipatory responses to food reward in the OFC after glucose intake (Heni et al., 2015)

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Cell Metabolism, 3 (3), 153165

In a clinical trial with 959 patients treated with OZEMPIC 1 mg or OZEMPIC 2 mg as add-on to metformin with or without sulfonylurea treatment for 40 weeks, no new safety signals were identified