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A study released last year by the National Institutes of Health found that once patients go off medications for weight loss, the average weight gain rebound is about two-thirds of the total weight loss

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The Zepbound (tirzepatide) label recommends switching to a non-oral birth control method, or adding a barrier method, for 4 weeks after starting Zepbound and for 4 weeks after each dose increase

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These methods are ideal for those who prefer to avoid surgery and medications