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Before her weight release journey, Lizzo tried a GLP-1, but she told Gayle that it wasnt successful, because of her fear of needles.

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You can increase it through fiber-rich foods, exercise, and sleepbut some people need medication to reach their goals

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As of early 2026, several potent single, dual, and triple incretin receptor agonists are in Phase 2/3 trials for MASH including : Survodutide : A dual glucagon (GCGR)/GLP-1 receptor agonist that has shown significant MASH resolution in Phase 2 trials