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If you would have asked any of these companies ten years ago, how durable is this revenue stream, and how durable are the profits from the revenue stream

It is even possible that the insulin-stimulating, glucagon-suppressing effects of the peptide or a more active synthetic analogue may be useful in the treatment of non-insulin-dependent diabetes, in which both impaired insulin release in response to glucose and persistent hyperglucagonemia are thought to be key pathophysiological abnormalities' (Kreymann, Ghattei, Williams, Bloom)

Mounjaro received FDA approval in 2022 for the treatment of type 2 diabetes in adults

To ensure maximum therapeutic efficacy, the oral regimen also follows a step-up titration (starting at 3mg, moving to 7mg, and settling at the maximum strength)