glp-1 novo Novo, Lilly buoyed by fast-growing drug sales Ozempic is first GLP-1 drug

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In the pancreas, this binding stimulates glucose-dependent insulin secretion from beta cells while suppressing inappropriate glucagon release from alpha cells

American Diabetes Association, 9

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However, one of the earliest studies, performed more than 15 years ago, administered the GLP-1 receptor agonist exendin-4 to db/db mice, a model of T2D (56)

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