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An almond-based low carbohydrate diet improves depression and glycometabolism in patients with type 2 diabetes through modulating gut microbiota and glp-1: a randomized controlled trial

Studies and clinical trials have shown that semaglutide also has anti-inflammatory benefits, as well as possible benefits for cardiovascular, liver, and kidney health

Thereafter, depending on the effects of the medication and clinical requirements, the dosage may need to be increased to the maximum dose of 2mg or 2.4mg per week

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A comprehensive meta-analysis of 11 trials involving 85,373 participants demonstrated that GLP-1 RAs reduced composite kidney outcomes by 18% (HR 0.82, 95% CI 0.730.93), kidney failure by 16% (HR 0.84, 0.720.99), MACEs by 13% (HR 0.87, 0.810.93), and all-cause death by 12% (HR 0.88, 0.830.93) in participants with type 2 diabetes [94,95]

Supplemental Table 2 summarizes information relating to the risk for retained gastric contents and aspiration in association with upper GI endoscopy