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Mean HbA 1c decreased from 7.69% to 7.07% in the sitagliptin/metformin group (adjusted mean, 0.62%
How GLP-1 Signaling Affects Brain Chemistry GLP-1 receptors exist throughout the central nervous system, not just in the digestive tract

Dementia and Alzheimer's are experiencing a shift in the way we understand the science and treat the disease manifestations
Lean mass percentage increases, which improves metabolic rate and creates a more favorable environment for maintaining weight loss long term

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10.1056/NEJMoa1603827 [DOI] [PMC free article] [PubMed] [Google Scholar] 5.Marso SP, Bain SC, Consoli A, et al