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Strategies like resistance training and high-quality protein intake are essential to maintain muscle during therapy

Variability in CNS penetrance, receptor signaling bias, and the potential for neuropsychiatric side effects warrant careful patient selection and compound-specific evaluation

References 1.Brennan PN, Tavabie OD, Li W, et al

Some investigators have characterized Alzheimer's disease as "type 3 diabetes" due to observed insulin resistance in the brain, though this terminology remains controversial and is not universally accepted

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