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We also found that CB0313.1 modulated gut microbiota composition, characterized by a decreased ratio of Firmicutes to Bacteroidetes, reduced Allobaculum bacteria that were abundant in HF diabetic mice and increased butyrate-producing bacteria

Methods We selected individuals aged 45 years and older already treated with metformin living in Lombardy, Italy, and then split them into two groups if they initiated GLP-1 RAs or other antidiabetic drugs, between 2019 and 2021

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Retatrutide is an investigational triple-hormone receptor agonist (GLP-1, GIP, and glucagon receptors) that demonstrates superior weight loss efficacy compar...

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