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This makes it a particularly logical addition for people transitioning off tirzepatide or semaglutide who want to maintain some GLP-1 pathway support without the full potency and cost of injectable GLP-1 agonists

For some patients, compounded semaglutide offers more flexible dosing or a cost-conscious alternative while maintaining therapeutic benefits

2023 Aug 1;334:302306

A.ZaccardiF.KhuntiK.WebbD

The relative benefits of canagliflozin for cardiovascular outcomes were similar in individuals across the spectrum of eGFR levels (155) DECLARETIMI 58 Trial The effect of dapagliflozin on cardiovascular events has been reported (156)