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Constipation and fatigue occasionally occur

It is a pain at my right hip and down my lateral right thigh

Author CB received lecture fees and served as a consultant for Takeda, MSD, Ferring, Abbvie, Galapagos and Janssen

Clinical trials show Saxendas potential for substantial weight loss, with participants losing up to 10% of their body weight in a year when combined with lifestyle changes like dietary adjustments and regular exercise

The review concludes with evidence-based recommendations for future investigations, prioritizing target validation studies, standardized clinical trial protocols, and personalized treatment paradigms

Conclusions In sum, the findings illustrate that adding bupropion/naltrexone therapy to GLP-1 analog monotherapy results in additional weight loss, even in those with an initially poor response to the monotherapy