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Only Saxenda is reimbursed under State schemes, and only for patients with BMI 35, prediabetes and high cardiovascular risk, under a strict HSE Managed Access Protocol

Oral semaglutide tablets achieve roughly 0.4% to 1% bioavailability

[DOI] [PubMed] [Google Scholar] 68.Yamazaki Y., Painter M.M., Bu G., Kanekiyo T

It is a carefully engineered peptide that maintains its three-dimensional shape only under specific conditions

Diabetes Obes Metab 2017;19:1233-41.PubMed 28