gip and glp-1 receptor agonist New strategies for the treatment of obesity metabolic dysfunctions Understand GLP-1/GIP Dual Agonist Tirzepatide
Description
As discussed below, the development of unimolecular multi-agonists that stimulate GLP-1 receptors and other receptors such as GIP receptors and glucagon receptors (GCGR) can have beneficial effects on metabolism and increase metabolic rate at tolerable doses [57]
Lancet , 404(10469), 2278-2298
doi: 10.1002/(ISSN)1096-9136 [DOI] [PubMed] [Google Scholar] 28
Several theories exist: The additive effects theory suggests that GIP and GLP-1 work through partially independent pathways
10.1038/s41366-025-01790-w 30
Eliaschewitz, F
