retatrutide clinical trial results obesity ⭐️topline from TRIUMPH-1, a Phase 3 evaluating #retatrutide, an investigational GIP / GLP-1 / glucagon triple hormone receptor agonist, in adults with or “overweight” Incretin-based therapies for the treatment
Description
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This effect has been observed both in vitro and in vivo
Table 2 Major clinical outcomes after matching
Conclusions Our study identified genetic proxies of GLP-1R-based agonists and demonstrated their causal effects on reducing the risk of MASLD and complications including liver cancer and CVD, probably by improving hyperlipidemia and insulin resistance and partly independent of the weight-loss effect
doi: 10.3390/nu16060857
