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Given the narrative nature of this review, a double-blind screening process was not applied, which is acknowledged as a limitation

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However, the Glu 138 -Phe 143 sequence clearly has -helical propensity, which is in agreement with the recent crystal structure of the homologous glucagon receptor TM domain showing an extracellular -helical extension of TM1 20

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Healthcare providers should counsel patients on expiration-date vigilance and proper documentation of first-use dates