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Nrregaard PK, Deryabina MA, Tofteng Shelton P, Fog JU, Daugaard JR, Eriksson P-O, et al

233.Centers for Disease Control and Prevention

Rinsing is strongly recommended

Therefore, drug delivery targeting the extracellular region of target receptors faces several insurmountable challenges, including (1) competitive interference from endogenous ligands or antibodies at the target and (2) pseudotarget or target loss caused by shedding or mutation of the extracellular region, which significantly inhibits drug efficacy and may pose safety concerns

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