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The European Union and the United States follow distinct frameworks, with India adopting a risk-based regulatory approach that may require extensive quality, safety, and clinical data

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In this article we review the most relevant data exploring the mechanisms involved in the effects of GLP-1RAs in the brainadipocyte axis.

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Comprehensive assessments included body weight, 2-D echocardiography, invasive hemodynamics, exercise capacity as well as cardiac and hepatic fibrosis and lipid deposition