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Dudley Lamming, a prominent researcher in the field of aging and metabolism

In contrast, a study comparing nateglinide with metformin demonstrated that metformin was more effective in lowering A1c levels (45)

GLP-1 may exert its effects locally via the vagus nerve before being degraded by DPP-4 in circulation

In a 12-week study of 91 patients with chronic renal insufficiency, 37 patients with moderate renal insufficiency were randomized to JANUVIA 50 mg daily, while 14 patients with the same magnitude of renal impairment were randomized to placebo

doi: 10.1056/NEJMoa2404881 34

provides further evidence supporting the use of GLP-1 agonists as a weight management tool in primary school-aged children