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GLP-based weight loss treatments are part of a class of medications that help regulate appetite and blood sugar levels

In opposite to ghrelin, GLP-1 agonism appears to reduce caloric intake by preferentially targeting consumption of both fat and sugar-rich palatable foods

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A study published in Clinical Therapeutics found that oral semaglutide was more cost-effective than injectable semaglutide in more than 50% of the model simulations, offering similar health benefits at a lower cost

Susana Monereo destaca la trascendencia de estos avances: "Los frmacos actuales son un hito, pues modulan a nivel cerebral los mecanismos de regulacin del hambre y la saciedad, ofreciendo as un nuevo paradigma en el manejo de la obesidad." Los tratamientos farmacolgicos modernos para la obesidad incluyen agentes que actan directamente sobre los centros de hambre y saciedad en el cerebro y alteran las vas metablicas para reducir el almacenamiento de grasa y aumentar el gasto energtico

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