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Wegovy has FDA approval for treating obesity in overweight adults who have at least one weight-related health issue
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Serum neurofilament indicates that DBS surgery can cause neuronal damage whereas stimulation itself does not
Unfortunately, this synergy is lost in prolonged hyperglycaemic states due to selective dysfunction in GIP signallingdownregulation of GIPR mRNA and accelerated receptor degradationwhereas sensitivity to GLP-1 remains intact [22, 23]
