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GLP-1 receptor activation slows gastric emptying, reduces appetite by acting on hypothalamic satiety centres, and stimulates glucose-dependent insulin secretion from pancreatic beta cells

Front Immunol 2016;7:394.ArticlePubMedPMC 10

In contrast, semaglutide acts as a glucagon-like peptide-1 receptor agonist (GLP-1 RA), modulating immune responses, reducing inflammation, and preserving gut barrier integrity

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J Neurosurg Anesthesiol, 29:400-405

muciniphila facilitates L-aspartate transportation in the gut-liver axis for the activation of the liver kinase B1 (LKB1)-AMPK pathway and increases lipid oxidation, thereby ameliorating liver steatosis (Rao et al., 2021)