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The aim of the present review is to examine the cellular processes underlying the actions of these new, highly significant classes of peptide receptor agonists

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GLP-1 (Glucagon-like peptide-1) plays a crucial role in managing blood sugar levels, reducing appetite, and supporting weight loss by influencing insulin and glucagon production.

By including all English-language studies on muscle mass loss during GLP-1RA therapy in T2D and obesity from major scientific databases and clinical trial registries, this narrative review synthesizes the current knowledge on the epidemiology and mechanisms of muscle loss in diabetes and obesity, with a focus on the impact of GLP-1RAs therapy

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