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In combination with metformin, JANUVIA provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo with metformin (Table 7)

What Happens After 3 Months

6 Similarly, as GLP-1RAs significantly reduced the risk of MACE, mortality from CV causes, when compared with placebo, ADA has suggested that these medications should be used in patients with underlying cardiovascular disease

2018Mar;9(2):262264

Because it is a newer, patent-protected drug, there is currently no cheap generic version available, and experts don't expect one until the early 2030s

And as recently as April, industry giant Pfizer halted its development of a GLP-1 competitor following reports of drug-induced liver injury