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Dietary changes, reduced fluid intake, and gastrointestinal side effects (nausea, vomiting, diarrhoea) may lead to concentrated urine with stronger odour

Pham TK, et al

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Park said he doubts semaglutide or tirzepatide will prove harmful, but wonders whether they will preserve quality of life at 75 or 80, when appetite is already irregular and muscle wasting accelerates

Some individuals get caught in a cycle of not eating due to nausea, which worsens the symptoms and further reduces the likelihood of eating