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( Shivers KY, Amador N, Abrams L, Hunter D, Jenab S, Quiones-Jenab V

Limited data mostly from case-control studies are available to assess whether citicoline (CDP-choline) might improve cognitive performance in subjects with AD or PD, and studies to date have generally been labeled as poor in quality (84)

These signals converge to activate the NLRP3 inflammasome, a multiprotein complex that drives the maturation of IL-1 and IL-18, sustaining chronic inflammation [16]

[DOI] [PubMed] [Google Scholar] 84.Lekshmi PC, Arimboor R, Indulekha PS, Menon AN

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Accordingly, the clinical presentations regarding liver involvement include a wide spectrum, ranging from asymptomatic subtle morphological changes, simple acute self-limited hepatitis-like illness to autoimmune-like hepatitis, or even recurrent jaundice (in the presence of haemolysis), cirrhosis with or without portal hypertension and even acute liver failure