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5.4 Use in Women of Childbearing Potential Because of the risk to the fetus of decreased IQ and major congenital malformations (including neural tube defects), which may occur very early in pregnancy, valproate should not be administered to a woman of childbearing potential unless the drug is essential to the management of her medical condition

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Therefore, we hypothesized that oral L-serine treatment could reprogram the transcriptomic and proteomic landscape of systemic immune cells, thereby modulating neuroimmune communication

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