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This hormone plays a role in insulin sensitivity, blood sugar control, and appetite suppression
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In the cardiovascular system, GLP-1RAs improve post-myocardial infarction remodeling by enhancing Akt/GSK-3 phosphorylation and downregulating profibrotic and inflammatory factors such as procollagen, TGF-3 and interleukins (156)

Table 1 RET Mutation Statusa Table 2 VEGFR, vascular endothelial growth factor receptor

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[70] found in vivo and in vitro studies that GLP-1 and its analog exendin-4 were able to induce an increase in ABCA1 mRNA, increase the expression of apo AI mRNA and promoter, thereby increasing apo AI secretion, indicating that GLP-1 in hepatocytes may mediate the outflow of intracellular cholesterol to apo AI through the ABCA1 pathway
