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Based on the structure of Tepotinib, we introduced chiral restriction conformation and hydrogen isotope deuterium to improve its metabolic stability, and synthesized a new structure of small molecule inhibitor 1D228

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Fernndez-Arjona MDM, Navarro JA, Lpez-Gambero AJ, de Ceglia M, Rodrguez M, Rubio L, Rodrguez de Fonseca F, Barrios V, Chowen JA, Argente J, et al

Signaling in eryptosis The main pathways of eryptosis signaling are summarized in Fig

Third, we did not measure serum IGF-1 binding protein (IGF-1BP)
