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In female rats, early-life Mn overexposure disrupted hormonal production and led to abnormal reproductive tissue development (Kim et al., 2012)

Human umbilical cord mesenchymal stem cells-derived Exosomal microRNA-451a represses epithelialmesenchymal transition of hepatocellular carcinoma cells by inhibiting ADAM10

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GSSG is then reduced back to GSH through interaction with glutathione reductase (the normal ratio of GSH/GSSG is about 100:1), using NAPDH as a cofactor (Couto et al., 2016

137 (1 Suppl): 223S228S

Michael AJ, Alexopoulos C, Pontiki EA, Hadjipavlou-Litina DJ, Saratsis P, Ververidis HN, Boscos CM