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Science 356 , (2017)

High vitamin B12 levels are not typically dangerous in themselves, as B12 is water-soluble and excess is naturally excreted

Patient reports do not consistently show this pattern

The liver and kidneys then convert it into its active hormonal form, calcitriol , which binds to vitamin D receptors in cells and regulates over 1,000 gene expressions related to bone health, immunity, and cellular function

Macrophages play a key role in tissue repair and regeneration
