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But they come with significant drawbacks: high cost, injection site reactions, increased infection risk due to immune suppression, and the development of anti-drug antibodies over time that can reduce efficacy

Wu Y, Zhang L, Li S, et al

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B12 injections are medically indicated for individuals with a diagnosed B12 deficiency or conditions that impair B12 absorption, such as pernicious anemia, Crohns disease, celiac disease, or a history of gastric bypass surgery

This method of fortifying food enables an increase in cobalamin content by utilizing unusual sources and obtaining the necessary daily consumption levels of vitamin B 12 through small amounts of fermented goods