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In those studies, no significant toxic effects have been reported

One bisamidate to advance to clinical trials is CS-917, a bis-alanine ethyl ester-protected phosphonate, which is an inhibitor of fructose 1,6-bisphosphatase [83]

PMID 20727946

In vivo analysis of oligodendrocyte lineage development in postnatal FGF2 null mice
