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Effects of Nigella sativa supplementation on blood parameters and anthropometric indices in adults: a systematic review on clinical trials

Although milk yield did not exhibit a significant response to Met supplementation, there was a tendency for an increase of 0.28 kg/d and 0.31 kg/d in cows supplemented with HMTBa and Mepron, respectively (Zanton et al., 2014)

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Conversely, the depletion of intracellular GSH through the use of buthionine sulphoximine led to a significant increase in the secretion of TNF-alpha and IL-8

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Thus, each animal acts as its own control, and any differences in measures obtained must be due to preparation condition