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doi: 10.1104/pp.010625 92 RouhierN.CerveauD.CouturierJ.ReichheldJ

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[DOI] [PubMed] [Google Scholar] 27.Weitz JI, Lensing AWA, Prins MH, et al

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Biochem J 417:113 Ramsay RR (2019) Electron carriers and energy conservation in mitochondrial respiration

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The lanthanides are defined by having f-block electron orbitals, and these elements are physiologically alien in vertebrates Case reports of neurologic damage (often permanent) and encephalopathy (sometimes fatal) incriminate small doses of gadolinium in profound biologic sequelae

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This review synthesizes key findings on the pathways dual mechanisms: moderate activation mitigates hyperglycemia-induced mesangial apoptosis, while chronic overactivation exacerbates renal fibrosis, podocyte injury, and tubular dysfunction

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Accurately interpreting studies requires relying on the division math (Total mg Total ml = mg per ml) rather than assuming the two measurements are interchangeable

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