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Genetic and pharmacological eosinophil depletion led to an enhanced Th1 response, polarization towards M1-like macrophages and resolution of clinical disease, despite an unexpected simultaneous upregulation of IL-4

For example, if initial plasma stability testing shows that an acid-sensitive linker hydrolyzes too quickly, researchers may modify electron substituents or peptide sequence length before conducting a second round of testing

doi: 10.1136/bcr-2018-228337 100 JoshiP.TurolaE.RuizA.BergamiA.LiberaD

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[PubMed] [Google Scholar] 241.Yokoyama A, Takagi T, Ishii H, Wada N, Maruyama K, Takagi S, Hayashida M

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