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This toxicity can lead to a predisposition to inflammatory (autoimmune) diseases including Alzheimers, MS, Parkinsonism, diabetes, chronic fatigue syndrome (CFS), chronic pain syndromes, cardiovascular misadventures, viral insult, cancers and rapid aging

Nature 444:847853 Coelho M, Oliveira T, Fernandes R (2013) Biochemistry of adipose tissue: an endocrine organ

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3.1.1.2 The non-canonical pathway Lipopolysaccharide (LPS) from the outer membrane of attenuated Salmonella is directly detected by cytosolic Caspase-4/5 in humans and Caspase-11 in mice